Differentiation Protocol-Dependent Variability in hiPSC-Derived Endothelial Progenitor Functionality
Stern, B., Meng, S., Larsen, B., Brock, A., Zoldan, J. (2025)
Regenerative Engineering and Translational Medicine
Access Online
A mathematical model for predicting the spatiotemporal response of breast cancer cells treated with doxorubicin
Miniere, H. , Lima ,E., Lorenzo ,G., Hormuth ,D., Ty ,S., Brock, A., Yankeelov, T. (2024).
Cancer Biology & Therapy
Access Online
Pycashier: cash in on DNA barcode tags.
Morgan, D., Brock, A. (2024)
Journal of Open Source Software
Access Online
Computational identification of surface markers for isolating distinct subpopulations from heterogeneous cancer cell populations
Gardner, A.L., Jost, T.A., Morgan, D., Brock, A. (2024)
npj Systems Biology and Applications
Access Online
Genetic variation drives cancer cell adaptation to ECM stiffness
Wang, T.-C., Sawhney, S., Morgan, D., Bennett, R. L., Rashmi, R., Estecio, M. R., Brock, A., Singh, I., Baer, C. F., Licht, J. D., Lele, T. P. (2024)
Proceedings of the National Academy of Sciences
Access Online
Cellular barcoding tracks heterogeneous clones through selective pressures and phenotypic transitions
Howland K, Brock A. (2023)
Trends Cancer
Access Online
Modeling collective cell behavior in cancer: perspectives from an interdisciplinary conversation
Adler F, Anderson A.R.A., Bhushan A, Bogdan P, Bravo-Cordero JJ, Brock A, Chen Y, Cukierman E, DelGiorno KE, Denis GV, Ferrall-Fairbanks M, Gartner Z, Germain R, Gordon DM, Hunter G, Jolly MK, Karacosta LG, Mythreye K, Katira P, Kulkarni RP, Kutys ML, Lander AD, Laughney AM, Levine H, Lou E; Lowenstein PR, Masters KS, Pe'er D, Peyton SR, Platt MO, Purvis JE, Quon G, Richer JK, Riddle NC, Rodriguez A, Snyder JC, Szeto GL, Tomlin CJ, Yanai I, Zervantonakis I, Dueck HR. (2023)
Cell Systems
Access Online
Quantification of long-term doxorubicin response dynamics in breast cancer cell lines to direct treatment schedules
Howard GR, Jost TA, Yankeelov TE, Brock A (2022)
PLOS Computational Biology
Access Online
Integration of quantitative methods and mathematical approaches for the modeling of cell proliferation dynamics
Cotner M*, Meng S*, De Santiago C, Gardner A, Jost T, Brock A. (2022)
American Journal of Physiology: Cell Physiology
Access Online
Functionalized Lineage Tracing for the Study and Manipulation of Heterogeneous Cell Populations
Gardner A*, Morgan D*, Al’Khafaji A, Brock A. (2022)
Biomedical Engineering Technologies.
Access Online
Applications of high-resolution clone tracking technologies in cancer
Morgan D, Jost TA, DeSantiago C, Brock, A. (2021)
Current Opinion in Biomedical Engineering
Access Online
An experimental-mathematical approach to predict tumor cell growth as a function of glucose availability in breast cancer cell lines
Yang J, Virostko J, Hormuth DA, Liu J, Brock A, Kowalski J, Yankeelov TE (2021)
PLOS One
Access Online
Multifunctional barcoding with ClonMapper enables high-resolution study of clonal dynamics during tumor evolution and treatment
Gutierrez C*, Al’Khafaji AM*, Brenner E*, Johnson KE, Gohil SH, Lin Z, Knisbacher BA, Durrett RE, Li S, Parvin S, Biran A, Zhang W, Rassenti L, Kipps TJ, Livak KJ, Neuberg D, Letai A, Getz G, Wu CJ, Brock A. (2021)
Nature Cancer
Access Online
A time-resolved experimental–mathematical model for predicting the response of glioma cells to single-dose radiation therapy
Liu J, Hormuth DA II, Davis T, Yang J, McKenna MT, Jarrett AM, Enderling H, Brock A, Yankeelov TE (2021)
Integrative Biology
Access Online
Integrating quantitative assays with biologically-based mathematical modeling for predictive oncology
Kazerouni AS, Gadde M, Gardner A, Hormuth DA, Jarrett AM, Johnson KE, Lima EABF, Lorenzo G, Phillips C, Brock A, Yankeelov TE (2020)
iScience
Access Online
Integrating multimodal data sets into a mathematical framework to describe and predict therapeutic resistance in cancer
Johnson K, Howard G, Morgan D, Brenner E, Gardner A, Durrett R, Mo W, Al’Khafaji A, Sontag E, Jarrett A, Yankeelov T, Brock A (2020)
IOP Science Physical Biology
Access Online
A hybrid model of tumor growth and angiogenesis: In silico experiments
Phillips CM, Lima EABF, Woodall RT, Brock A, Yankeelov TE (2020)
PLOS One
Access Online
Single cell transcriptome profiling of the human alcohol-dependent brain
Brenner E, Tiwari GR, Liu Y, Brock A, Mayfield RD. (2020)
Human Molecular Genetics
Access Online
Emerging Concepts and Tools in Cell Mechanomemory
Lele TP, Brock A, Peyton S. (2019)
Annals of Biomedical Engineering
Access Online
Cancer cell population growth kinetics at low densities deviate from exponential growth model and suggest an Allee effect
Johnson K, Howard G, Mo W, Strasser M, Lima, E ABF, Huang S, Brock A. (2019)
PLOS Biology
Access Online
Single-cell RNA sequencing of lung adenocarcinoma reveals heterogeneity of immune response–related genes
Ma KY, Schonnesen AA, Brock A, Van Den Berg C, Eckhardt SG, Liu Z, Jiang N. (2019)
JCI Insight
Access Online
Mathematical models of tumor cell proliferation: A review of the literature
Jarrett AM, Lima E ABF, Hormuth DA, McKenna MT, Feng X, Ekrut DA, Resende AC, Brock A, Yankeelov TE. (2018)
Expert Review of Anticancer Therapy
Access Online
A Phenotypic Basis for Matrix Stiffness-Dependent Chemoresistance of Breast Cancer Cells to Doxorubicin
Joyce MH, Lu C, James E, Hegab R, Allen S, Suggs L, Brock A. (2018)
Frontiers in Oncology
Access Online
Control of Lineage-Specific Gene Expression by Functionalized gRNA Barcodes
Al’Khafaji A, Deatherage D, Brock A. (2018)
ACS Synthetic Biology
Access Online
A multi-state model of chemoresistance to characterize phenotypic dynamics in breast cancer
Howard GR, Johnson KE, Ayala AR, Yankeelov TE, Brock A. (2018)
Nature Scientific Reports
Access Online
Precision Medicine with Imprecise Therapy: Computational Modeling for Chemotherapy in Breast Cancer
McKenna MT, Weis JA, Brock A, Quaranta V, Yankeelov TE. (2018)
Translational Oncology
Access Online
Precision Oncology: Between Vaguely Right and Precisely Wrong
Brock A and Huang, S. (2017)
Cancer Research
Access Online
Novel Nanomaterials Enable Biomimetic Models of the Tumor Microenvironment
Joyce MH, Allen S, Suggs L, Brock A. (2017)
Journal of Nanotechnology
Access Online
Intraductal Delivery to Rabbit Mammary Gland
Clark A, Bird N, Brock A. (2017)
Journal of Visualized Experiments
Access Online
Control of cancer formation by intrinsic genetic noise and microenviromental cues
Brock A, Krause S, Ingber DE. (2015)
Nature Reviews Cancer
Access Online
Nanoparticle targeting of anti-cancer drugs that alter intracellular signaling or influence the tumor microenvironment
Kanapathipillai M, Brock A, Ingber D. (2014)
Advanced Drug Delivery Reviews
Access Online
Silencing HoxA1 by Intraductal Injection of siRNA Lipidoid Nanoparticles Prevents Mammary Tumor Progression in Mice
Brock A, Krause S, Li H., Kowalski M, Goldberg M, Collins JJ, Ingber DE. (2014)
Science Translational Medicine
Access Online
Non-Darwinian dynamics in therapy-induced cancer drug resistance
Pisco, A.*, Brock, A.*, Zhou, J. et al (2013)
Nature Communications
Access Online
Intraductal Injection for Localized Drug Delivery to the Mouse Mammary Gland
Krause S, Brock A, Ingber DE. (2013)
Journal of Visualized Experiments
Access Online
Cellular Reprogramming: A New Technology Frontier in Pharmaceutical Research
Brock, A., Goh, HT., Yang, B. et al. (2012)
Pharmaceutical Research
Access Online
Non-genetic heterogeneity — a mutation-independent driving force for the somatic evolution of tumours
Brock, A., Chang, H. & Huang, S. (2009)
Nature Reviews Genetics
Access Online
Control of the direction of lamellipodia extension through changes in the balance between Rac and Rho activities
Brock AL, Ingber DE. (2006)
Molecular & Cellular Biomechanics
Access Online
High betweenness proteins in the yeast protein interaction network
Joy MP, Brock A, Ingber, DE, Huang S. (2005)
BioMed Research Online
Access Online
Identification of a distinct class of cytoskeleton-associated mRNAs using microarray technology
Brock, A., Huang, S. & Ingber, D.E. (2003)
BMC Cell Biology
Access Online
Geometric determinants of directional cell motility revealed using microcontact printing
Brock A, Chang E, Ho CC, LeDuc, P, Jiang X, Whitesides GM, Ingber DE. (2003)
Langmuir
Access Online
Directional control of lamellipodia extension by constraining cell shape and orienting cell tractional forces
Parker KK, Brock AL, Brangwynne C, Mannix, RJ, Wang N, Ostuni E, Geisse, NA, Adams JC, Whitesides GM, Ingber DE. (2002)
The FASEB Journal
Access Online
The S. cerevisiae Mag1 3-methyladenine DNA glycosylase modulates susceptibility to homologous recombination
Hendricks CA, Razlog M, Matsuguchi T, Goyal A, Brock AL, Engelward BP. (2002)
DNA Repair
Access Online
Isolation of high molecular length DNA: alfalfa, pea, rice, sorghum, soybean and spinach
Bennett PV, Hada M, Hidema J, Lepre A, Pope LC, Quaite FE, Sullivan JH, Takayanagi S, Sutherland JC, Sutherland BM. (2001)
Crop Science
Access Online
A robust, inexpensive filter for blocking UVC radiation in broad-spectrum ‘UVB’ lamps
Lepre A, Sutherland JC, Trunk JG, Sutherland BM. (1998)
Journal of Photochemistry and Photobiology B: Biology
Access Online
Stern, B., Meng, S., Larsen, B., Brock, A., Zoldan, J. (2025)
Regenerative Engineering and Translational Medicine
Access Online
A mathematical model for predicting the spatiotemporal response of breast cancer cells treated with doxorubicin
Miniere, H. , Lima ,E., Lorenzo ,G., Hormuth ,D., Ty ,S., Brock, A., Yankeelov, T. (2024).
Cancer Biology & Therapy
Access Online
Pycashier: cash in on DNA barcode tags.
Morgan, D., Brock, A. (2024)
Journal of Open Source Software
Access Online
Computational identification of surface markers for isolating distinct subpopulations from heterogeneous cancer cell populations
Gardner, A.L., Jost, T.A., Morgan, D., Brock, A. (2024)
npj Systems Biology and Applications
Access Online
Genetic variation drives cancer cell adaptation to ECM stiffness
Wang, T.-C., Sawhney, S., Morgan, D., Bennett, R. L., Rashmi, R., Estecio, M. R., Brock, A., Singh, I., Baer, C. F., Licht, J. D., Lele, T. P. (2024)
Proceedings of the National Academy of Sciences
Access Online
Cellular barcoding tracks heterogeneous clones through selective pressures and phenotypic transitions
Howland K, Brock A. (2023)
Trends Cancer
Access Online
Modeling collective cell behavior in cancer: perspectives from an interdisciplinary conversation
Adler F, Anderson A.R.A., Bhushan A, Bogdan P, Bravo-Cordero JJ, Brock A, Chen Y, Cukierman E, DelGiorno KE, Denis GV, Ferrall-Fairbanks M, Gartner Z, Germain R, Gordon DM, Hunter G, Jolly MK, Karacosta LG, Mythreye K, Katira P, Kulkarni RP, Kutys ML, Lander AD, Laughney AM, Levine H, Lou E; Lowenstein PR, Masters KS, Pe'er D, Peyton SR, Platt MO, Purvis JE, Quon G, Richer JK, Riddle NC, Rodriguez A, Snyder JC, Szeto GL, Tomlin CJ, Yanai I, Zervantonakis I, Dueck HR. (2023)
Cell Systems
Access Online
Quantification of long-term doxorubicin response dynamics in breast cancer cell lines to direct treatment schedules
Howard GR, Jost TA, Yankeelov TE, Brock A (2022)
PLOS Computational Biology
Access Online
Integration of quantitative methods and mathematical approaches for the modeling of cell proliferation dynamics
Cotner M*, Meng S*, De Santiago C, Gardner A, Jost T, Brock A. (2022)
American Journal of Physiology: Cell Physiology
Access Online
Functionalized Lineage Tracing for the Study and Manipulation of Heterogeneous Cell Populations
Gardner A*, Morgan D*, Al’Khafaji A, Brock A. (2022)
Biomedical Engineering Technologies.
Access Online
Applications of high-resolution clone tracking technologies in cancer
Morgan D, Jost TA, DeSantiago C, Brock, A. (2021)
Current Opinion in Biomedical Engineering
Access Online
An experimental-mathematical approach to predict tumor cell growth as a function of glucose availability in breast cancer cell lines
Yang J, Virostko J, Hormuth DA, Liu J, Brock A, Kowalski J, Yankeelov TE (2021)
PLOS One
Access Online
Multifunctional barcoding with ClonMapper enables high-resolution study of clonal dynamics during tumor evolution and treatment
Gutierrez C*, Al’Khafaji AM*, Brenner E*, Johnson KE, Gohil SH, Lin Z, Knisbacher BA, Durrett RE, Li S, Parvin S, Biran A, Zhang W, Rassenti L, Kipps TJ, Livak KJ, Neuberg D, Letai A, Getz G, Wu CJ, Brock A. (2021)
Nature Cancer
Access Online
A time-resolved experimental–mathematical model for predicting the response of glioma cells to single-dose radiation therapy
Liu J, Hormuth DA II, Davis T, Yang J, McKenna MT, Jarrett AM, Enderling H, Brock A, Yankeelov TE (2021)
Integrative Biology
Access Online
Integrating quantitative assays with biologically-based mathematical modeling for predictive oncology
Kazerouni AS, Gadde M, Gardner A, Hormuth DA, Jarrett AM, Johnson KE, Lima EABF, Lorenzo G, Phillips C, Brock A, Yankeelov TE (2020)
iScience
Access Online
Integrating multimodal data sets into a mathematical framework to describe and predict therapeutic resistance in cancer
Johnson K, Howard G, Morgan D, Brenner E, Gardner A, Durrett R, Mo W, Al’Khafaji A, Sontag E, Jarrett A, Yankeelov T, Brock A (2020)
IOP Science Physical Biology
Access Online
A hybrid model of tumor growth and angiogenesis: In silico experiments
Phillips CM, Lima EABF, Woodall RT, Brock A, Yankeelov TE (2020)
PLOS One
Access Online
Single cell transcriptome profiling of the human alcohol-dependent brain
Brenner E, Tiwari GR, Liu Y, Brock A, Mayfield RD. (2020)
Human Molecular Genetics
Access Online
Emerging Concepts and Tools in Cell Mechanomemory
Lele TP, Brock A, Peyton S. (2019)
Annals of Biomedical Engineering
Access Online
Cancer cell population growth kinetics at low densities deviate from exponential growth model and suggest an Allee effect
Johnson K, Howard G, Mo W, Strasser M, Lima, E ABF, Huang S, Brock A. (2019)
PLOS Biology
Access Online
Single-cell RNA sequencing of lung adenocarcinoma reveals heterogeneity of immune response–related genes
Ma KY, Schonnesen AA, Brock A, Van Den Berg C, Eckhardt SG, Liu Z, Jiang N. (2019)
JCI Insight
Access Online
Mathematical models of tumor cell proliferation: A review of the literature
Jarrett AM, Lima E ABF, Hormuth DA, McKenna MT, Feng X, Ekrut DA, Resende AC, Brock A, Yankeelov TE. (2018)
Expert Review of Anticancer Therapy
Access Online
A Phenotypic Basis for Matrix Stiffness-Dependent Chemoresistance of Breast Cancer Cells to Doxorubicin
Joyce MH, Lu C, James E, Hegab R, Allen S, Suggs L, Brock A. (2018)
Frontiers in Oncology
Access Online
Control of Lineage-Specific Gene Expression by Functionalized gRNA Barcodes
Al’Khafaji A, Deatherage D, Brock A. (2018)
ACS Synthetic Biology
Access Online
A multi-state model of chemoresistance to characterize phenotypic dynamics in breast cancer
Howard GR, Johnson KE, Ayala AR, Yankeelov TE, Brock A. (2018)
Nature Scientific Reports
Access Online
Precision Medicine with Imprecise Therapy: Computational Modeling for Chemotherapy in Breast Cancer
McKenna MT, Weis JA, Brock A, Quaranta V, Yankeelov TE. (2018)
Translational Oncology
Access Online
Precision Oncology: Between Vaguely Right and Precisely Wrong
Brock A and Huang, S. (2017)
Cancer Research
Access Online
Novel Nanomaterials Enable Biomimetic Models of the Tumor Microenvironment
Joyce MH, Allen S, Suggs L, Brock A. (2017)
Journal of Nanotechnology
Access Online
Intraductal Delivery to Rabbit Mammary Gland
Clark A, Bird N, Brock A. (2017)
Journal of Visualized Experiments
Access Online
Control of cancer formation by intrinsic genetic noise and microenviromental cues
Brock A, Krause S, Ingber DE. (2015)
Nature Reviews Cancer
Access Online
Nanoparticle targeting of anti-cancer drugs that alter intracellular signaling or influence the tumor microenvironment
Kanapathipillai M, Brock A, Ingber D. (2014)
Advanced Drug Delivery Reviews
Access Online
Silencing HoxA1 by Intraductal Injection of siRNA Lipidoid Nanoparticles Prevents Mammary Tumor Progression in Mice
Brock A, Krause S, Li H., Kowalski M, Goldberg M, Collins JJ, Ingber DE. (2014)
Science Translational Medicine
Access Online
Non-Darwinian dynamics in therapy-induced cancer drug resistance
Pisco, A.*, Brock, A.*, Zhou, J. et al (2013)
Nature Communications
Access Online
Intraductal Injection for Localized Drug Delivery to the Mouse Mammary Gland
Krause S, Brock A, Ingber DE. (2013)
Journal of Visualized Experiments
Access Online
Cellular Reprogramming: A New Technology Frontier in Pharmaceutical Research
Brock, A., Goh, HT., Yang, B. et al. (2012)
Pharmaceutical Research
Access Online
Non-genetic heterogeneity — a mutation-independent driving force for the somatic evolution of tumours
Brock, A., Chang, H. & Huang, S. (2009)
Nature Reviews Genetics
Access Online
Control of the direction of lamellipodia extension through changes in the balance between Rac and Rho activities
Brock AL, Ingber DE. (2006)
Molecular & Cellular Biomechanics
Access Online
High betweenness proteins in the yeast protein interaction network
Joy MP, Brock A, Ingber, DE, Huang S. (2005)
BioMed Research Online
Access Online
Identification of a distinct class of cytoskeleton-associated mRNAs using microarray technology
Brock, A., Huang, S. & Ingber, D.E. (2003)
BMC Cell Biology
Access Online
Geometric determinants of directional cell motility revealed using microcontact printing
Brock A, Chang E, Ho CC, LeDuc, P, Jiang X, Whitesides GM, Ingber DE. (2003)
Langmuir
Access Online
Directional control of lamellipodia extension by constraining cell shape and orienting cell tractional forces
Parker KK, Brock AL, Brangwynne C, Mannix, RJ, Wang N, Ostuni E, Geisse, NA, Adams JC, Whitesides GM, Ingber DE. (2002)
The FASEB Journal
Access Online
The S. cerevisiae Mag1 3-methyladenine DNA glycosylase modulates susceptibility to homologous recombination
Hendricks CA, Razlog M, Matsuguchi T, Goyal A, Brock AL, Engelward BP. (2002)
DNA Repair
Access Online
Isolation of high molecular length DNA: alfalfa, pea, rice, sorghum, soybean and spinach
Bennett PV, Hada M, Hidema J, Lepre A, Pope LC, Quaite FE, Sullivan JH, Takayanagi S, Sutherland JC, Sutherland BM. (2001)
Crop Science
Access Online
A robust, inexpensive filter for blocking UVC radiation in broad-spectrum ‘UVB’ lamps
Lepre A, Sutherland JC, Trunk JG, Sutherland BM. (1998)
Journal of Photochemistry and Photobiology B: Biology
Access Online